We've used titanium dioxide safely for decades. However, recently its safety was called into question. 
 
At CRIS, we've explored the safety of titanium dioxide for nearly half a decade, including conducting double-blind research to test the safety of food-grade titanium dioxide (E171). Our study shows that when exposed to food-grade titanium dioxide in normal conditions, research animals did not experience adverse health outcomes.
 
It's important to emphasize that in a National Institutes of Health study, experimental animals were exposed to titanium dioxide in amounts as high as 5% of their diet for a lifetime and showed no evidence of adverse effects. 
 
A handful of studies greatly influenced the decisions made by the European Food Safety Authority (EFSA). Unfortunately, these studies did not consider that titanium dioxide exposure comes from food, not drinking water. Additionally, CRIS researchers could not reproduce the adverse outcomes identified by the studies through typical food ingestion. Regardless, the EFSA banned E171 as a food ingredient and for use in other capacities in the summer of 2022.
 
In 2022, the United States, United Kingdom, and Canada maintained that the scientific evidence supports that titanium dioxide (E171) is safe for humans to use and consume.

Ultimately, most experts advise moderation, as titanium dioxide is typically found in processed foods that come with their own health risks.

Titanium dioxide, a naturally occurring oxide of titanium, is widely recognized for its exceptional properties and versatility in various industries. Among its numerous applications, the production of tires stands out as a crucial area where titanium dioxide plays an indispensable role. This article aims to explore the significance of wholesale titanium dioxide in the tire manufacturing sector, emphasizing its properties, benefits, and the overall impact on product quality.

That came after a 2021 report from an expert panel at the European Food Safety Authority, which reviewed data on titanium dioxide safety. The panel said it couldn’t rule out concerns that the food additive might be able to damage DNA and possibly lead to cancer. They explained that after you eat something that has titanium dioxide in it, your body absorbs low levels of its particles – but the particles can build up as you eat more foods with this additive.

In a lawsuit filed last week, a consumer alleged that Skittles were unfit for human consumption because the rainbow candy contained a known toxin – an artificial color additive called titanium dioxide.